1. What is infertility and what is sterility?

2. What is the infertility frequency?

3. Which are the main reasons?

4. What is the suitable frequency of sexual relations to obtain a gestation?

5. When is it necessary to consult a specialist?

6. Which tests are made at the first consult?

7. What is the usual treatment?

8. How big is the risk of getting a multiple pregnancy?

9. How much does the treatment cost?

10. How long will it take to obtain a pregnancy?

11. Is it dangerous to have more than one treatment?

12. Are drugs used in assisted reproductive techniques dangerous?

13. Can the sex of the offspring be chosen?

14. Does Spanish law permit single women to have these treatments?

15. Can characteristics of the donor be chosen?

16. Are donation and reception of ova or semen completely anonymous?

17. Can disabled have children by assisted reproductive techniques?

18. And seropositives?



1. What is infertility and what is sterility?

Although both terms seem similar they differ clearly in. While in sterility no gestation is obtained, in infertility there is pregnancy, but it doesn’t end up with normality. Starting from this difference we reach the following classification:

  • Primary sterility: no consequence of pregnancy after one and a half year’s
    relations
  • Secondary sterility: no consequence of pregnancy during the following 2 to
    3 years of gestation and delivery of the first baby
  • Primary infertility: a pregnancy is obtained, but this doesn’t end up with a
    normal newborn
  • Secondary infertility: a pregnancy is obtained, but this doesn’t end up with a
    normal newborn after a normal pregnancy and delivery.

2. What is the infertility frequency?

Couples, with infertility problems, that wish a gestation, range between 15% and 17% although the absolute impossibility in succeeding it is situated between 1% and 2% ON the whole.

3. Which are the main reasons?


There are several kinds of reasons: medical, psychical and immunitary, as well as general and sociocultural.

Among the medical reasons we find ovarian (15-38%), tubal (20-35%), uterine (5-10%) and cervical (3-30%) in the woman. Disorders at a testicular level, include alterations in excretory viae because of duct obstruction, accessory glandes pathology, ejaculation alterations, immunological caused alterations, erection alterations and structural or functional defects of the spermatozoa in the male.

Between 0,1% and 28% are psychical reasons (diseases or conflicts) that alter the reproduction capacity affecting hypothalamus.

Isoinmunization, capacity of response before an extraneous body, creates antibodies in 48% of the women, obstructing a good penetration of spermatozoa in cervical mucus, restraining fecundation.

Among general causes we find: extreme obesity, anorexia nervosa, thyroid alterations, drug or medicament abuses, alcohol, tobacco, lack of certain vitamins, stress and bad coital technique
.
The most indicated sociocultural factor is making plans to have children at a late age, seeing as the possibility of a pregnancy begins to decrease after 35 years.

There is also a kind of sterility of unknown origin, where there is no reason to be found after having studied the couple.

4. What is the suitable frequency of sexual relations to obtain a gestation?


There is no adequate frequency, although it is established that the possibilities of gestation increase during roughly the middle of the cycle, when ovulation occurs. The best way to have sexual relations in the couple is by natural frequency, since obsession with ovulation control might create counter-productive anxiety for gestation.

5. When is it necessary to consult a specialist?

Consulting a specialist is recommended when there is no gestation after a year’s sexual relations.

6. Which tests are made at the first consult?

At the first consult laboratory tests are made to reject pathologies that might dissuade pregnancy, and to understand the immunitary state of the patients to identify infectious diseases that could be transmitted to the fetus.

These tests include a complete hemogram, group and Rh factor, biochemistry and a hemostasia study. Serology, hepatitis markers, systematic urine and uroculture if appropriate.

Semen analysis and capacitation test.

7. What is the usual treatment?

The kind of treatment depends on each patient and it is chosen after each particular case study, always deciding the simplest solution applicable.

If we are talking about a painful process, it depends on the woman’s sensibility bearing in mind the possible use of anesthesia.

8. How big is the risk of getting a multiple pregnancy?

In accordance with the national rates a twin pregnancy is around 14% and a triple is less than 3%.

9. How much does the treatment cost?


Economic investment depends on the kind of infertility and the treatment to be used, such as the frequency of its application.

10. How long will it take to obtain a pregnancy?

There is neither a certain time nor an established limit. It depends on the woman’s age and the technique used, among other factors.

11. Is it dangerous to have more than one treatment?

No.

12. Are drugs used in assisted reproductive techniques dangerous?

After the achieved studies to verify side effects of used hormonal drugs for ovarian stimulation, there has only been found two: excessive ovarian response (as an exception) and multiple pregnancy (that increases to 12%).

13. Can the sex of the offspring be chosen?

According to present Spanish legislation, genetic manipulation is only permitted with authorised therapeutic purposes, which means that neither sex nor any other genetic character can be chosen.

14. Does Spanish law permit single women to have these treatments?

Yes.

15. Can characteristics of the donor be chosen?


The medical team chooses characteristics of the donor according to characteristics of the beneficiary couple.

16. Are donation and reception of ova or semen completely anonymous?

Yes, donation both of semen ova is absolutely anonymous.

17. Can disabled have children by assisted reproductive techniques?

The couple, where one or both suffer from a disability, and in addition there is an infertility problem, can benefit from assisted reproductive techniques just like the rest of couples. A totally different situation is produced when disability requires use of a technique to obtain gestation; for example, a medullar injury in the male. In this case there are methods to get semen that allow us to introduce it into the vagina. If semen is altered, artificial insemination has to be done proceeding its positioning, into the woman’s uterine after it has been prepared.

18. And seropositives?


The couples with discordance HIV who want to have a child can also benefit from assisted reproductive techniques.

The following are the alternatives of available reproduction methods for couples with discordance HIV:

  • Artificial insemination of the woman with washed sperm of her HIV infected
    partner: this method involves introduction of the sperm into the uterine, after
    it has been washed to remove seminal plasma and non-spermatozoa
    cells. After achieving a sequence of cleanings the semen undergoes
    analyses of PCR to reject presence of viral burden
  • In vitro fertilisation with prepared semen of the HIV infected partner 
  • Artificial insemination with donor’s semen